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Kazuhiro Takuma Selected Research

Treatment-Resistant Schizophrenia

1/2017Differential gene expression profiles in neurons generated from lymphoblastoid B-cell line-derived iPS cells from monozygotic twin cases with treatment-resistant schizophrenia and discordant responses to clozapine.

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Kazuhiro Takuma Research Topics

Disease

13Schizophrenia (Dementia Praecox)
10/2021 - 02/2007
13Cognitive Dysfunction
01/2017 - 01/2006
13Alzheimer Disease (Alzheimer's Disease)
02/2016 - 04/2004
9Autistic Disorder (Autism)
11/2019 - 02/2013
8Autism Spectrum Disorder
01/2021 - 01/2012
8Mental Disorders (Mental Disorder)
08/2019 - 01/2011
7Attention Deficit Disorder with Hyperactivity (Attention Deficit Hyperactivity Disorder)
01/2016 - 07/2010
5Psychotic Disorders (Schizoaffective Disorder)
06/2011 - 02/2007
4Parkinson Disease (Parkinson's Disease)
05/2012 - 03/2007
4Mitochondrial Diseases (Mitochondrial Disease)
11/2009 - 08/2002
3Pain (Aches)
01/2014 - 05/2013
3Memory Disorders (Memory Loss)
02/2013 - 06/2008
3Neurodegenerative Diseases (Neurodegenerative Disease)
08/2011 - 10/2008
2Neurodevelopmental Disorders
01/2020 - 01/2017
2Acute Pain
11/2013 - 05/2013
2Bipolar Disorder (Manic Depressive Psychosis)
02/2012 - 01/2011
2Alcoholism (Alcohol Abuse)
02/2012 - 01/2011
1Intellectual Disability (Idiocy)
01/2020
1Major Depressive Disorder (Major Depressive Disorders)
08/2017
1AIDS-Related Complex (ARC)
01/2017
1Treatment-Resistant Schizophrenia
01/2017
1Epilepsy (Aura)
09/2015
1Chronic Pain
11/2013
1Hyperalgesia
11/2013
1Treatment-Resistant Depressive Disorder
02/2013
1Dyskinesias (Dyskinesia)
05/2012
1Body Weight (Weight, Body)
01/2012
1Neuroblastoma
08/2011

Drug/Important Bio-Agent (IBA)

9Valproic Acid (Depakote)FDA LinkGeneric
01/2019 - 01/2012
8Serotonin (5 Hydroxytryptamine)IBA
08/2017 - 07/2010
5Norepinephrine (Noradrenaline)FDA LinkGeneric
05/2014 - 07/2010
5Methamphetamine (Desoxyn)FDA LinkGeneric
01/2009 - 02/2007
4Pharmaceutical PreparationsIBA
08/2019 - 02/2013
4Galantamine (Galanthamine)FDA LinkGeneric
02/2016 - 01/2011
4Methylphenidate (Ritalin)FDA LinkGeneric
01/2016 - 07/2010
4Amyloid beta-PeptidesIBA
11/2009 - 04/2004
3Antipsychotic Agents (Antipsychotics)IBA
11/2019 - 01/2011
3Clozapine (Clozaril)FDA LinkGeneric
01/2017 - 01/2006
3Atomoxetine Hydrochloride (Strattera)FDA LinkGeneric
01/2016 - 07/2010
3Dopamine (Intropin)FDA LinkGeneric
01/2016 - 07/2010
3Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP)IBA
10/2014 - 06/2010
3CatecholaminesIBA
04/2014 - 07/2010
35-HT1A Serotonin ReceptorIBA
01/2014 - 05/2013
3Nitric Oxide (Nitrogen Monoxide)FDA Link
08/2011 - 10/2008
2Oxytocin (Pitocin)FDA LinkGeneric
01/2021 - 11/2017
2Messenger RNA (mRNA)IBA
01/2017 - 07/2009
2Dizocilpine Maleate (Dizocilpine)IBA
11/2016 - 03/2007
2EnzymesIBA
11/2016 - 04/2005
2Donepezil (Aricept)FDA LinkGeneric
02/2016 - 07/2005
2Sodium-Calcium ExchangerIBA
09/2015 - 08/2011
2Neurotransmitter Agents (Neurotransmitter)IBA
08/2015 - 01/2011
2Glutamic Acid (Glutamate)FDA Link
02/2013 - 01/2012
2MGS 0028IBA
02/2013 - 01/2012
2Levodopa (L Dopa)FDA LinkGeneric
05/2012 - 03/2007
21- Methyl- 4- phenyl- 1,2,3,6- tetrahydropyridine (MPTP)IBA
12/2011 - 10/2008
2Therapeutic UsesIBA
06/2011 - 01/2006
2GABA-B ReceptorsIBA
01/2009 - 12/2008
2Hormones (Hormone)IBA
06/2008 - 03/2008
1Dopamine D2 Receptors (Dopamine D2 Receptor)IBA
10/2021
1DNA Transposable Elements (Element, IS)IBA
01/2020
1Protein Kinase D2IBA
11/2019
1Selective Serotonin Reuptake Inhibitors (Serotonin Reuptake Inhibitors)IBA
08/2017
1MicroRNAs (MicroRNA)IBA
01/2017
1Brain-Derived Neurotrophic Factor (BDNF)IBA
01/2017
1Cyclooxygenase 1IBA
11/2016
1N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA
11/2016
1Prostaglandin D2IBA
11/2016
1Histone Deacetylase InhibitorsIBA
10/2016
1Cholinesterase Inhibitors (Anticholinesterases)IBA
02/2016
1Rivastigmine (Exelon)FDA LinkGeneric
02/2016
1Butyric Acid (Butanoic Acid)IBA
11/2014
12,3- dioxo- 6- nitro- 7- sulfamoylbenzo(f)quinoxaline (NBQX)IBA
06/2014
1Amphetamine (Amfetamine)FDA LinkGeneric
05/2014
1Desipramine (Pertofrane)FDA LinkGeneric
04/2014
1LigandsIBA
01/2014
1osemozotanIBA
11/2013
1Duloxetine Hydrochloride (Cymbalta)FDA Link
08/2013
1Venlafaxine Hydrochloride (Effexor)FDA LinkGeneric
08/2013
1Acetic Acid (Vinegar)FDA LinkGeneric
05/2013
1Histones (Histone)IBA
02/2013
1CorticosteroneIBA
02/2013
17-nitroindazoleIBA
05/2012
1pimagedine (aminoguanidine)IBA
05/2012
1NG-Nitroarginine Methyl Ester (L-NAME)IBA
05/2012
1Nitric Oxide Synthase Type I (Neuronal Nitric Oxide Synthase)IBA
05/2012
1Oxidopamine (6 Hydroxydopamine)IBA
05/2012
1Ginkgo biloba extract (Rokan)IBA
01/2012
1Placental ExtractsIBA
01/2012
1SEA 0400IBA
12/2011
1U 0126 (UO 126)IBA
08/2011
1MitogensIBA
08/2011
1Phosphotransferases (Kinase)IBA
08/2011
1Proteins (Proteins, Gene)FDA Link
08/2011
1SB 203580IBA
08/2011
1JNK Mitogen-Activated Protein KinasesIBA
08/2011

Therapy/Procedure

2Ovariectomy (Oophorectomy)
01/2012 - 03/2008
1Spinal Injections
11/2013
1Ligation
11/2013
1Therapeutics
05/2012
1Estrogen Replacement Therapy
01/2012